I think it depends on which method you use to decrypt.
I have a Digital Devices DVB-S2 Cine 6.5 Twin Tuner (expensive...€150) but works flawlessly, installed the card rebooted and scanned...worked out of the box, but I use a Softcam for decryption.
To my knowledge, there are very few hardware CAMS that support Multi-channel decryption.