Unfortunately the inside of a PC case is very noisy from an electrical perspective, there's a lot of components that can (and do) cause interference so if your signal is less than perfect you will notice issues.
Anecdotally I've noticed the opposite, our DVB-T feed to the house is patch, we have a TV in the kitchen that on some days struggles to keep a stable picture whilst my TVHeadend/Kodi setup works almost perfectly from the same feed.
Further anecdotally I've just switched from the closed source to open source TBS DVB drivers and noticed the signal strength/quality has improved by about 20% over the closed source variants so drivers do impact the equation too.
In short, it's not an exact science unfortunately.